We finally got a universal remote for the video setup at home. We’re not early adopters and this is a pretty mainstream category, so quite likely you know all about it. In case you don’t, just wanted to say that Logitech Harmony 650 is a super-nice product and works really well for us.
Our setup is totally vanilla: a big 2010 Insignia TV, a new Motorola cable box, a middle-aged Toshiba DVD player, and an elderly NAD amp. Some of the remotes were broken, others claimed to be universal, ha-ha-ha. I’d tried universals a few years back and they basically just didn’t work for whatever I’d had.
Anyhow, you program the Logitech on your Mac or PC with a nice little program that lives in the browser and talks to the USB. It asks you a set of plain-English questions that seem about the minimum possible, then blasts your setup into the remote. It pretty well Just Works.